Absolute Automation supports "Exchange Online" Plan 1 and Plan 2, as well as all three "Office 365 Enterprise" Editions. IS.com does not support "Office 365 Small and Midsize Business" Edition.
See the supported "Exchange Online" plans here:
See the supported "Enterprise Editions" here:
For reference, here is a comparison of features offered:
You may need to establish transport rules for your Microsoft product(s). Visit the Microsoft Technet article here: